| WTA New York | 08/19 17:00 | 25 | Karolina Muchova v Viktoria Kuzmova | View | |
| WTA New York | 08/19 14:00 | 26 | Kristie Ahn v Karolina Muchova | Cancelled | |
| Wimbledon Women | 07/09 13:45 | 27 | [8] Elina Svitolina v Karolina Muchova [68] | 7-5,6-4 | |
| Wimbledon Women | 07/08 12:00 | 26 | [68] Karolina Muchova v Karolina Pliskova [3] | 4-6,7-5,13-11 | |
| Wimbledon Women | 07/05 12:25 | 25 | [68] Karolina Muchova v Anett Kontaveit [20] | 7-6,6-3 | |
| Wimbledon Women | 07/03 10:00 | 24 | [85] Madison Brengle v Karolina Muchova [68] | 3-6,4-6 | |
| Wimbledon Women | 07/01 12:05 | 23 | [68] Karolina Muchova v Aleksandra Krunic [113] | 7-5,6-2 | |
| WTA Hertogenbosch | 06/11 11:20 | 25 | [61] Alison Riske v Karolina Muchova [68] | 6-7,6-3,6-2 | |
| French Open Women | 05/30 10:55 | 24 | [116] Irina-Camelia Begu v Karolina Muchova [73] | 1-6,6-3,6-4 | |
| French Open Women | 05/28 10:45 | 23 | [73] Karolina Muchova v Anett Kontaveit [17] | 3-6,6-2,6-2 | |
| WTA Prague | 05/04 09:00 | 29 | [146] Jil Teichmann v Karolina Muchova [106] | 7-6,3-6,6-4 | |
| WTA Prague | 05/03 09:00 | 28 | [105] Bernarda Pera v Karolina Muchova [106] | 2-6,5-7 | |
| WTA Prague | 05/02 11:25 | 27 | [106] Karolina Muchova v Natalia Vikhlyantseva [113] | 6-3,6-4 | |
| WTA Prague | 05/01 12:25 | 26 | [83] Jennifer Brady v Karolina Muchova [106] | 4-6,6-3,6-7 | |
| WTA Prague | 04/30 12:55 | 25 | [106] Karolina Muchova v Iga Swiatek [95] | 4-6,6-1,6-4 | |
| WTA Prague | 04/30 09:00 | 29 | Karolina Muchova v Barbora Strycova | Cancelled | |
| World Group Play Offs | 04/21 11:25 | - | Karolina Muchova v Leylah Annie Fernandez | Cancelled | |
| 2019 Fed Cup | 04/20 11:30 | - | [106] Karolina Muchova v Rebecca Marino [184] | 6-3,6-0 | |
| WTA Monterrey | 04/05 01:40 | 26 | [5] Angelique Kerber v Karolina Muchova [109] | 6-3,6-4 | |
| WTA Monterrey | 04/02 21:30 | 25 | [206] Shilin Xu v Karolina Muchova [109] | 4-6,7-5,3-6 | |
| WTA Miami | 03/22 20:10 | 24 | [113] Karolina Muchova v Angelique Kerber [4] | 6-3,3-6,3-6 | |
| WTA Miami | 03/21 20:40 | 23 | [113] Karolina Muchova v Nao Hibino [119] | 6-3,6-3 | |
| WTA Miami | 03/20 15:40 | 45 | [116] Marie Bouzkova v Karolina Muchova [113] | 4-6,3-6 | |
| WTA Miami | 03/18 20:20 | 44 | [113] Karolina Muchova v Vitalia Diatchenko [106] | 7-6,6-1 | |
| WTA Doha | 02/14 12:30 | 27 | [7] Elina Svitolina v Karolina Muchova [132] | 6-4,6-2 | |
| WTA Doha | 02/13 12:30 | 26 | [31] Su-Wei Hsieh v Karolina Muchova [132] | 2-6,4-6 | |
| WTA Doha | 02/12 14:45 | 25 | [132] Karolina Muchova v Samantha Stosur [73] | 6-4,6-2 | |
| WTA Doha | 02/12 13:30 | - | Karolina Muchova v Caroline Wozniacki | Cancelled | |
| WTA Doha | 02/11 12:30 | 54 | [167] Liudmila Samsonova v Karolina Muchova [132] | 1-6,6-3,1-6 | |
| WTA Doha | 02/10 12:30 | 46 | [133] Karolina Muchova v Kristyna Pliskova [90] | 6-3,4-6,6-4 |