| Challenger Las Vegas | 10/26 19:30 | 25 | Steve Johnson v Ivo Karlovic | Cancelled | |
| ATP Indian Wells | 10/06 18:00 | 19 | [174] Emilio Gomez v Ivo Karlovic [200] | 6-3,7-6 | |
| ATP Indian Wells | 10/05 18:00 | 14 | [231] Brayden Schnur v Ivo Karlovic [200] | 6-4,6-7,6-7 | |
| US Open | 08/30 16:50 | 23 | [7] Andrey Rublev v Ivo Karlovic [221] | 6-3,7-6,6-3 | |
| US Open | 08/27 19:25 | 19 | [131] Yuichi Sugita v Ivo Karlovic [223] | 3-6,6-7 | |
| US Open | 08/26 23:10 | 15 | [223] Ivo Karlovic v Hugo Dellien [137] | 7-5,6-7,6-2 | |
| US Open | 08/25 19:50 | 14 | [223] Ivo Karlovic v Nikola Milojevic [160] | 6-4,7-6 | |
| ATP Washington | 07/31 20:45 | 14 | [203] Ivo Karlovic v Illya Marchenko [158] | 3-6,7-6,3-6 | |
| ATP Los Cabos | 07/21 01:40 | 25 | [63] Jordan Thompson v Ivo Karlovic [200] | 6-4,7-5 | |
| ATP Newport | 07/14 17:05 | 26 | [37] Alexander Bublik v Ivo Karlovic [210] | 7-6,4-6,6-1 | |
| ATP Newport | 07/13 15:00 | 25 | [210] Ivo Karlovic v Bernabe Zapata Miralles [120] | 6-7,6-1,6-4 | |
| Wimbledon | 06/22 13:05 | 14 | [156] Roman Safiullin v Ivo Karlovic [190] | 6-3,6-4 | |
| Challenger Tallahassee | 04/20 17:40 | 25 | [169] Ivo Karlovic v Bjorn Fratangelo [221] | 6-7,7-6,6-7 | |
| ATP Miami | 03/23 15:45 | 19 | [120] Mackenzie McDonald v Ivo Karlovic [172] | 7-6,6-4 | |
| ATP Miami | 03/22 15:40 | 14 | [206] Tatsuma Ito v Ivo Karlovic [172] | 3-6,6-7 | |
| ATP Delray Beach | 01/10 23:00 | 26 | [293] Roberto Quiroz v Ivo Karlovic [148] | 6-2,6-4 | |
| ATP Delray Beach | 01/08 23:00 | 25 | [148] Ivo Karlovic v Pablo Andujar [59] | 6-3,5-7,6-4 | |
| ATP Cologne | 10/10 09:00 | 64 | [131] Ivo Karlovic v Marc Polmans [122] | 1-6,4-6 | |
| French Open | 09/23 11:20 | 15 | [226] Benjamin Bonzi v Ivo Karlovic [131] | 6-3,7-6 | |
| French Open | 09/21 13:40 | 14 | [230] Noah Rubin v Ivo Karlovic [130] | 6-7,4-6 | |
| US Open | 09/01 23:30 | 23 | [126] Ivo Karlovic v Richard Gasquet [51] | 6-7,6-7,1-6 | |
| Matchplay 120 | 06/12 13:00 | 1 | [276] JC Aragone v Ivo Karlovic [124] | 7-6,7-5 | |
| Challenger Calgary | 02/27 19:15 | 26 | [124] Ivo Karlovic v Geoffrey Blancaneaux [271] | 6-7,4-6 | |
| Challenger Calgary | 02/26 03:00 | 25 | [124] Ivo Karlovic v Evan King [427] | 7-6,6-4 | |
| ATP New York | 02/11 17:00 | 25 | [122] Ivo Karlovic v Jordan Thompson [63] | 3-6,6-7 | |
| ATP Pune | 02/03 10:00 | 25 | [149] Cedrik-Marcel Stebe v Ivo Karlovic [121] | 6-3,6-4 | |
| Australian Open | 01/23 05:25 | 24 | [10] Gael Monfils v Ivo Karlovic [124] | 4-6,7-6,6-4,7-5 | |
| Australian Open | 01/21 10:35 | 23 | [124] Ivo Karlovic v Vasek Pospisil [138] | 7-6,6-4,7-5 | |
| ATP Doha | 01/04 08:00 | 64 | [105] Jiri Vesely v Ivo Karlovic [95] | 6-7,6-3,6-2 | |
| Challenger Houston | 11/17 19:00 | 29 | [123] Marcos Giron v Ivo Karlovic [106] | 7-5,6-7,7-6 |