Stadium: Welsh-Ryan Arena Round: 1
Home Manager: Chris Collins Away Manager: Mike Brennan
| NCAAB | 2018/11/10 00:00 | American v George Mason | W | 78-75 |
| NCAAB | 2018/02/28 00:00 | American v Lafayette | L | 86-93 |
| NCAAB | 2018/02/24 19:00 | Bucknell v American | L | 80-61 |
| NCAAB | 2018/02/22 00:05 | American v Holy Cross | L | 64-70 |
| NCAAB | 2018/02/17 19:00 | Lafayette v American | L | 90-85 |
| NCAAB | 2018/02/15 00:00 | Boston U v American | W | 56-60 |
| NCAAB | 2018/02/10 19:00 | Lehigh v American | L | 80-78 |
| NCAAB | 2018/02/08 00:00 | Loyola Maryland v American | L | 72-69 |
| NCAAB | 2018/11/09 01:00 | New Orleans v Northwestern | W | 52-82 |
| NCAAB | 2018/03/01 23:30 | Northwestern v Penn State | L | 57-65 |
| NCAAB | 2018/02/26 00:30 | Northwestern v Iowa | L | 70-77 |
| NCAAB | 2018/02/23 00:00 | Wisconsin v Northwestern | L | 70-64 |
| NCAAB | 2018/02/20 00:00 | Maryland v Northwestern | L | 71-64 |
| NCAAB | 2018/02/17 19:00 | Michigan State v Northwestern | L | 65-60 |
| NCAAB | 2018/02/14 02:00 | Northwestern v Rutgers | L | 58-67 |
| NCAAB | 2018/02/10 17:00 | Northwestern v Maryland | L | 57-73 |