[27] BUF Sabres 1-5 NY Islanders [6] 2019-03-30 23:00
Stadium: Nassau Veterans Memorial Coliseum Round: 1
Home Manager: Barry Trotz Away Manager: Phil Housley
Head to Head
| NHL | 2019/02/13 00:00 | NY Islanders v BUF Sabres | W | 1-3 |
| NHL | 2018/12/31 23:00 | NY Islanders v BUF Sabres | L | 3-1 |
| NHL Pre-Season | 2018/09/28 23:00 | BUF Sabres v NY Islanders | W | 5-4 |
| NHL | 2018/02/09 00:00 | NY Islanders v BUF Sabres | W | 3-4 |
| NHL | 2017/12/28 00:00 | BUF Sabres v NY Islanders | L | 2-3 |
| NHL | 2017/10/07 23:00 | NY Islanders v BUF Sabres | L | 6-3 |
| NHL Pre-Season | 2017/09/29 23:00 | NY Islanders v BUF Sabres | L | 3-1 |
| NHL | 2017/04/02 19:00 | NY Islanders v BUF Sabres | L | 4-2 |
Home History
| NHL | 2019/03/28 23:00 | DET Red Wings v BUF Sabres | L | 5-4 |
| NHL | 2019/03/26 23:30 | BUF Sabres v OTT Senators | L | 0-4 |
| NHL | 2019/03/25 23:00 | BUF Sabres v NJ Devils | L | 1-3 |
| NHL | 2019/03/23 23:00 | BUF Sabres v MON Canadiens | L | 4-7 |
| NHL | 2019/03/20 23:00 | TOR Maple Leafs v BUF Sabres | L | 4-2 |
| NHL | 2019/03/17 21:00 | STL Blues v BUF Sabres | W | 3-4 |
| NHL | 2019/03/16 23:00 | BUF Sabres v CAR Hurricanes | L | 2-4 |
| NHL | 2019/03/14 23:00 | PIT Penguins v BUF Sabres | L | 5-0 |
Away History
| NHL | 2019/03/29 00:00 | NY Islanders v WIN Jets | W | 5-4 |
| NHL | 2019/03/26 23:00 | NY Islanders v CLB Blue Jackets | L | 0-4 |
| NHL | 2019/03/24 19:00 | ARZ Coyotes v NY Islanders | W | 0-2 |
| NHL | 2019/03/23 17:00 | NY Islanders v PHI Flyers | W | 4-2 |
| NHL | 2019/03/21 23:30 | NY Islanders v MON Canadiens | L | 0-4 |
| NHL | 2019/03/19 23:00 | BOS Bruins v NY Islanders | L | 5-0 |
| NHL | 2019/03/17 22:00 | NY Islanders v MIN Wild | W | 3-2 |
| NHL | 2019/03/16 17:00 | NY Islanders v DET Red Wings | L | 1-2 |
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