[9] John Isner 7-6,6-7,6-7 Reilly Opelka [89] 2019-02-17 00:00
Stadium: Stadium Court Round: 28 Ground: Hardcourt indoor
Head to Head
| Australian Open | 2019/01/14 02:55 | Reilly Opelka v John Isner | 7-6,7-6,6-7,7-6 |
Home History
| ATP New York | 2019/02/16 00:00 | John Isner v Jordan Thompson | 6-4,6-1 |
| ATP New York | 2019/02/14 00:30 | John Isner v Bernard Tomic | 7-6,6-4 |
| Australian Open | 2019/01/14 02:55 | Reilly Opelka v John Isner | 7-6,7-6,6-7,7-6 |
| ATP Auckland | 2019/01/08 23:00 | John Isner v Taylor Fritz | 6-7,6-7 |
| ATP World Tour Finals | 2018/11/16 14:00 | Alexander Zverev v John Isner | 7-6,6-3 |
| ATP World Tour Finals | 2018/11/14 20:00 | Marin Cilic v John Isner | 6-7,6-3,6-4 |
| ATP World Tour Finals | 2018/11/12 20:00 | Novak Djokovic v John Isner | 6-4,6-3 |
| ATP Paris | 2018/11/01 12:00 | Karen Khachanov v John Isner | 6-4,6-7,7-6 |
Away History
| ATP New York | 2019/02/15 21:50 | Guillermo Garcia-Lopez v Reilly Opelka | 3-6,4-6 |
| ATP New York | 2019/02/12 16:00 | Reilly Opelka v Adrian Mannarino | 2-6,7-6,6-4 |
| Challenger Dallas | 2019/02/10 01:35 | Mackenzie McDonald v Reilly Opelka | 6-4,7-6 |
| Challenger Dallas | 2019/02/08 21:35 | Reilly Opelka v Dominik Koepfer | 7-6,3-6,7-6 |
| Challenger Dallas | 2019/02/07 20:10 | Reilly Opelka v Thomaz Bellucci | 6-4,6-4 |
| Challenger Dallas | 2019/02/05 21:45 | Reilly Opelka v Jan Choinski | 4-6,6-3,6-4 |
| Australian Open | 2019/01/16 05:45 | Thomas Fabbiano v Reilly Opelka | 6-7,6-2,6-4,3-6,7-6 |
| Australian Open | 2019/01/14 02:55 | Reilly Opelka v John Isner | 7-6,7-6,6-7,7-6 |
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