[11] Carlisle 0-1 Leyton Orient [14] 2021-03-23 18:30
Stadium: Brunton Park Round: 23
Referee: James Bell Home Manager: Chris Beech Away Manager: Joel Joshua Frederick McAnuff
Head to Head
| England League 2 | 2019/10/26 14:00 | Leyton Orient v Carlisle | D | 1-1 |
| England League 2 | 2017/02/04 15:00 | Leyton Orient v Carlisle | W | 1-2 |
| England League 2 | 2016/09/10 14:00 | Carlisle v Leyton Orient | D | 2-2 |
| England League 2 | 2016/03/01 19:45 | Carlisle v Leyton Orient | D | 2-2 |
| England League 2 | 2015/09/29 18:45 | Leyton Orient v Carlisle | W | 1-2 |
Home History
| England League 2 | 2021/03/20 13:00 | Stevenage v Carlisle | L | 3-1 |
| England League 2 | 2021/03/16 19:30 | Mansfield v Carlisle | D | 1-1 |
| England League 2 | 2021/03/13 15:00 | Carlisle v Bradford | W | 3-1 |
| England League 2 | 2021/03/09 19:00 | Carlisle v Grimsby | D | 1-1 |
| England League 2 | 2021/03/06 15:00 | Morecambe v Carlisle | L | 3-1 |
| England League 2 | 2021/03/02 19:00 | Colchester v Carlisle | L | 2-1 |
| England League 2 | 2021/02/27 15:00 | Carlisle v Oldham | L | 1-3 |
| England League 2 | 2021/02/23 19:00 | Carlisle v Tranmere | L | 2-3 |
Away History
| England League 2 | 2021/03/20 13:00 | Newport County v Leyton Orient | W | 0-1 |
| England League 2 | 2021/03/13 13:00 | Leyton Orient v Scunthorpe | D | 1-1 |
| England League 2 | 2021/03/09 19:00 | Leyton Orient v Stevenage | D | 0-0 |
| England League 2 | 2021/03/06 13:00 | Exeter v Leyton Orient | L | 4-0 |
| England League 2 | 2021/03/02 19:00 | Grimsby v Leyton Orient | W | 0-1 |
| England League 2 | 2021/02/27 15:00 | Leyton Orient v Tranmere | L | 1-3 |
| England League 2 | 2021/02/23 19:00 | Bradford v Leyton Orient | L | 1-0 |
| England League 2 | 2021/02/20 15:00 | Leyton Orient v Port Vale | D | 1-1 |
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