| Uruguay Apertura Primera Women | 2021/09/19 23:00 | Nautico Women v 25 De Agosto Women | L | 3-2 |
| Uruguay Apertura Primera Women | 2021/09/11 21:00 | 25 De Agosto Women v Penarol Women | L | 1-3 |
| Uruguay Apertura Primera Women | 2021/09/04 21:00 | Layva Women v 25 De Agosto Women | L | 3-1 |
| Uruguay Apertura Primera Women | 2021/08/29 21:00 | 25 De Agosto Women v Union Sta.Rosa Women | W | 3-0 |
| Uruguay Apertura Primera Women | 2021/08/22 20:00 | Bohemios Women v 25 De Agosto Women | L | 2-0 |
| Uruguay Apertura Primera Women | 2021/08/14 23:00 | 25 De Agosto Women v Tao Club Women | L | 0-3 |
| Uruguay Apertura Primera Women | 2021/08/07 21:00 | Olimpia Women v 25 De Agosto Women | L | 3-0 |
| Uruguay Apertura Primera Women | 2021/08/01 21:00 | Juan Ferreira Women v 25 De Agosto Women | L | 3-0 |
| Uruguay Apertura Primera Women | 2021/09/18 20:30 | Club Banco Republica Women v Juan Ferreira Women | L | 1-3 |
| Uruguay Apertura Primera Women | 2021/09/11 19:30 | Club Banco Republica Women v Nautico Women | L | 1-3 |
| Uruguay Apertura Primera Women | 2021/09/04 21:00 | Club Banco Republica Women v Penarol Women | W | 3-0 |
| Uruguay Apertura Primera Women | 2021/08/28 18:00 | Layva Women v Club Banco Republica Women | W | 0-3 |
| Uruguay Apertura Primera Women | 2021/08/21 23:30 | Union Sta.Rosa Women v Club Banco Republica Women | W | 0-3 |
| Uruguay Apertura Primera Women | 2021/08/14 19:00 | Bohemios Women v Club Banco Republica Women | L | 3-1 |
| Uruguay Apertura Primera Women | 2021/08/08 18:00 | Tao Club Women v Club Banco Republica Women | W | 1-3 |
| Uruguay Apertura Primera Women | 2021/08/03 23:30 | Club Banco Republica Women v Olimpia Women | W | 3-1 |