| Uruguay Apertura Primera Women | 2021/09/11 21:00 | 25 De Agosto Women v Penarol Women | W | 1-3 |
| Uruguay Apertura Primera Women | 2021/10/10 21:30 | Penarol Women v Tao Club Women | L | 2-3 |
| Uruguay Apertura Primera Women | 2021/10/03 18:30 | Union Sta.Rosa Women v Penarol Women | W | 0-3 |
| Uruguay Apertura Primera Women | 2021/09/26 23:00 | Tao Club Women v Penarol Women | L | 3-0 |
| Uruguay Apertura Primera Women | 2021/09/18 23:00 | Penarol Women v Olimpia Women | L | 0-3 |
| Uruguay Apertura Primera Women | 2021/09/11 21:00 | 25 De Agosto Women v Penarol Women | W | 1-3 |
| Uruguay Apertura Primera Women | 2021/09/04 21:00 | Club Banco Republica Women v Penarol Women | L | 3-0 |
| Uruguay Apertura Primera Women | 2021/08/29 21:00 | Penarol Women v Nautico Women | L | 0-3 |
| Uruguay Apertura Primera Women | 2021/08/22 19:45 | Penarol Women v Juan Ferreira Women | L | 0-3 |
| Uruguay Apertura Primera Women | 2021/10/03 21:00 | 25 De Agosto Women v Layva Women | W | 1-0 |
| Uruguay Apertura Primera Women | 2021/09/26 20:00 | 25 De Agosto Women v Club Banco Republica Women | L | 2-3 |
| Uruguay Apertura Primera Women | 2021/09/19 23:00 | Nautico Women v 25 De Agosto Women | L | 3-2 |
| Uruguay Apertura Primera Women | 2021/09/11 21:00 | 25 De Agosto Women v Penarol Women | L | 1-3 |
| Uruguay Apertura Primera Women | 2021/09/04 21:00 | Layva Women v 25 De Agosto Women | L | 3-1 |
| Uruguay Apertura Primera Women | 2021/08/29 21:00 | 25 De Agosto Women v Union Sta.Rosa Women | W | 3-0 |
| Uruguay Apertura Primera Women | 2021/08/22 20:00 | Bohemios Women v 25 De Agosto Women | L | 2-0 |
| Uruguay Apertura Primera Women | 2021/08/14 23:00 | 25 De Agosto Women v Tao Club Women | L | 0-3 |