Stadium: Harry A. Gampel Pavilion
Home Manager: Dan Hurley Away Manager: Tony Stubblefield
| NCAAB | 2022/01/29 23:30 | Connecticut v DePaul | L | 57-50 |
| NCAAB | 2021/03/12 02:00 | DePaul v Connecticut | L | 60-94 |
| NCAAB | 2021/01/11 23:00 | Connecticut v DePaul | L | 60-53 |
| NCAAB | 2020/12/31 02:00 | DePaul v Connecticut | L | 61-82 |
| NCAAB | 2012/03/06 12:00 | Connecticut v DePaul | L | 81-67 |
| NCAAB | 2012/02/15 12:00 | Connecticut v DePaul | L | 80-54 |
| NCAAB | 2011/03/08 12:00 | Connecticut v DePaul | L | 97-71 |
| NCAAB | 2011/01/15 12:00 | DePaul v Connecticut | L | 62-82 |
| NCAAB | 2022/03/03 02:00 | Marquette v DePaul | W | 80-91 |
| NCAAB | 2022/02/27 22:00 | St Johns v DePaul | W | 94-99 |
| NCAAB | 2022/02/25 01:00 | DePaul v Georgetown | W | 68-65 |
| NCAAB | 2022/02/20 01:00 | DePaul v Seton Hall | L | 64-66 |
| NCAAB | 2022/02/18 03:00 | Creighton v DePaul | L | 71-59 |
| NCAAB | 2022/02/16 02:00 | Butler v DePaul | L | 73-71 |
| NCAAB | 2022/02/12 23:30 | DePaul v Providence | L | 73-76 |
| NCAAB | 2022/02/10 02:00 | Georgetown v DePaul | W | 74-82 |
| NCAAB | 2022/03/03 01:30 | Connecticut v Creighton | L | 62-64 |
| NCAAB | 2022/02/27 17:00 | Connecticut v Georgetown | W | 86-77 |
| NCAAB | 2022/02/23 01:00 | Villanova v Connecticut | W | 69-71 |
| NCAAB | 2022/02/19 17:00 | Xavier v Connecticut | W | 61-72 |
| NCAAB | 2022/02/17 01:30 | Seton Hall v Connecticut | W | 65-70 |
| NCAAB | 2022/02/13 17:00 | Connecticut v St Johns | W | 63-60 |
| NCAAB | 2022/02/12 00:00 | Connecticut v Xavier | L | 68-74 |
| NCAAB | 2022/02/08 23:30 | Marquette v Connecticut | W | 72-80 |