Stadium: John M. Belk Arena
Home Manager: Bob McKillop Away Manager: Dane Fischer
| NCAAB | 2021/12/02 00:00 | William & Mary v Navy | L | 56-75 |
| NCAAB | 2021/11/27 21:00 | William & Mary v Mary Baldwin | W | 87-50 |
| NCAAB | 2021/11/24 22:00 | William & Mary v Radford | L | 54-67 |
| NCAAB | 2021/11/21 22:00 | William & Mary v Howard | L | 76-82 |
| NCAAB | 2021/11/20 22:00 | Georgia State v William & Mary | L | 77-59 |
| NCAAB | 2021/11/17 00:00 | William & Mary v Norfolk State | L | 74-91 |
| NCAAB | 2021/11/13 00:00 | American v William & Mary | L | 74-62 |
| NCAAB | 2021/11/11 00:00 | William & Mary v Wake Forest | L | 59-77 |
| NCAAB | 2021/12/01 00:00 | Davidson v Charlotte U | W | 75-58 |
| NCAAB | 2021/11/27 19:00 | Robert Morris v Davidson | W | 70-88 |
| NCAAB | 2021/11/21 23:00 | Davidson v East Carolina | W | 76-67 |
| NCAAB | 2021/11/19 19:30 | Davidson v Pennsylvania | W | 72-60 |
| NCAAB | 2021/11/18 17:00 | Davidson v New Mexico State | L | 64-75 |
| NCAAB | 2021/11/14 01:30 | Davidson v San Francisco | L | 60-65 |
| NCAAB | 2021/11/10 00:00 | Delaware v Davidson | W | 71-93 |
| NIT | 2021/03/18 23:00 | NC State v Davidson | L | 75-61 |