Stadium: Jack Breslin Students Events Center
Home Manager: Tom Izzo Away Manager: Clayton Bates
| NCAAB | 2020/12/06 23:00 | Western Michigan v Michigan State | L | 61-79 |
| NCAAB | 2019/12/30 01:00 | Western Michigan v Michigan State | L | 62-95 |
| NCAAB | 2021/11/11 00:00 | Western Michigan v Hope Flying Dutchmen | W | 76-58 |
| NCAAB | 2021/03/06 00:00 | Eastern Michigan v Western Michigan | L | 64-63 |
| NCAAB | 2021/03/03 00:00 | Western Michigan v Northern Illinois | W | 73-63 |
| NCAAB | 2021/02/27 22:00 | Western Michigan v Toledo | L | 44-91 |
| NCAAB | 2021/02/25 17:00 | Miami Ohio v Western Michigan | L | 74-66 |
| NCAAB | 2021/02/17 00:00 | Kent State v Western Michigan | L | 76-69 |
| NCAAB | 2021/02/13 01:00 | Western Michigan v Buffalo | L | 54-86 |
| NCAAB | 2021/02/06 19:00 | Western Michigan v Central Michigan | W | 67-65 |
| NCAAB | 2021/11/10 00:00 | Kansas v Michigan State | L | 87-74 |
| NCAAB | 2021/03/19 02:19 | UCLA v Michigan State | L | 86-80 |
| NCAAB | 2021/03/11 16:30 | Michigan State v Maryland | L | 57-68 |
| NCAAB | 2021/03/07 21:30 | Michigan v Michigan State | W | 64-70 |
| NCAAB | 2021/03/05 00:00 | Michigan State v Michigan | L | 50-69 |
| NCAAB | 2021/03/03 01:00 | Indiana v Michigan State | W | 58-64 |
| NCAAB | 2021/02/28 19:00 | Michigan State v Maryland | L | 55-73 |
| NCAAB | 2021/02/26 02:00 | Ohio State v Michigan State | W | 67-71 |