| Guatemala Liga Nacional Women | 2021/10/11 00:00 | Deportivo Mixco Women v Antigua GFC Women | L | 0-1 |
| Guatemala Liga Nacional Women | 2021/09/15 17:00 | Antigua GFC Women v Deportivo Mixco Women | L | 1-0 |
| Guatemala Liga Nacional Women | 2021/05/03 00:00 | Deportivo Mixco Women v Antigua GFC Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2021/03/27 15:14 | Antigua GFC Women v Deportivo Mixco Women | L | 1-0 |
| Guatemala Liga Nacional Women | 2022/02/07 00:00 | Deportivo Mixco Women v CSD Barcena FF Women | W | 4-0 |
| Guatemala Liga Nacional Women | 2021/11/14 16:00 | Cobaneras FC Women v Deportivo Mixco Women | L | 2-0 |
| Guatemala Liga Nacional Women | 2021/10/25 00:10 | Deportivo Mixco Women v Pares Women | W | 3-0 |
| Guatemala Liga Nacional Women | 2021/10/11 00:00 | Deportivo Mixco Women v Antigua GFC Women | L | 0-1 |
| Guatemala Liga Nacional Women | 2021/10/02 18:00 | CSD Barcena FF Women v Deportivo Mixco Women | W | 0-1 |
| Guatemala Liga Nacional Women | 2021/09/26 17:11 | Santa Lucia Cotzumalguapa Women v Deportivo Mixco Women | L | 5-1 |
| Guatemala Liga Nacional Women | 2021/09/15 17:00 | Antigua GFC Women v Deportivo Mixco Women | L | 1-0 |
| Guatemala Liga Nacional Women | 2021/09/12 15:30 | Pares Women v Deportivo Mixco Women | W | 0-2 |
| Guatemala Liga Nacional Women | 2022/02/06 17:00 | Antigua GFC Women v Tunecas Women | D | 1-1 |
| Guatemala Liga Nacional Women | 2021/11/14 17:10 | Antigua GFC Women v Xinabajul Women | L | 0-4 |
| Guatemala Liga Nacional Women | 2021/11/07 02:00 | Xinabajul Women v Antigua GFC Women | L | 4-0 |
| Guatemala Liga Nacional Women | 2021/10/11 00:00 | Deportivo Mixco Women v Antigua GFC Women | W | 0-1 |
| Guatemala Liga Nacional Women | 2021/10/03 17:00 | Antigua GFC Women v Santa Lucia Cotzumalguapa Women | D | 0-0 |
| Guatemala Liga Nacional Women | 2021/09/26 15:00 | Pares Women v Antigua GFC Women | W | 0-3 |
| Guatemala Liga Nacional Women | 2021/09/19 16:00 | Antigua GFC Women v CSD Barcena FF Women | W | 3-0 |
| Guatemala Liga Nacional Women | 2021/09/15 17:00 | Antigua GFC Women v Deportivo Mixco Women | W | 1-0 |