| Guatemala Liga Nacional Women | 2022/03/27 21:00 | Antigua GFC Women v Deportivo Mixco Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2022/02/14 00:00 | Deportivo Mixco Women v Antigua GFC Women | W | 3-2 |
| Guatemala Liga Nacional Women | 2021/10/11 00:00 | Deportivo Mixco Women v Antigua GFC Women | L | 0-1 |
| Guatemala Liga Nacional Women | 2021/09/15 17:00 | Antigua GFC Women v Deportivo Mixco Women | L | 1-0 |
| Guatemala Liga Nacional Women | 2021/05/03 00:00 | Deportivo Mixco Women v Antigua GFC Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2021/03/27 15:14 | Antigua GFC Women v Deportivo Mixco Women | L | 1-0 |
| Guatemala Liga Nacional Women | 2022/04/25 00:00 | Deportivo Mixco Women v Tunecas Women | D | 0-0 |
| Guatemala Liga Nacional Women | 2022/04/03 17:00 | Deportivo Mixco Women v K’iche FC Women | W | 1-0 |
| Guatemala Liga Nacional Women | 2022/03/27 21:00 | Antigua GFC Women v Deportivo Mixco Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2022/03/06 17:00 | Tunecas Women v Deportivo Mixco Women | L | 3-1 |
| Guatemala Liga Nacional Women | 2022/02/27 02:00 | Deportivo Mixco Women v Deportivo Colomba Women | W | 3-0 |
| Guatemala Liga Nacional Women | 2022/02/20 01:00 | K’iche FC Women v Deportivo Mixco Women | L | 4-2 |
| Guatemala Liga Nacional Women | 2022/02/14 00:00 | Deportivo Mixco Women v Antigua GFC Women | W | 3-2 |
| Guatemala Liga Nacional Women | 2022/02/07 00:00 | Deportivo Mixco Women v CSD Barcena FF Women | W | 4-0 |
| Guatemala Liga Nacional Women | 2022/05/15 16:00 | Antigua GFC Women v FCF El Estor Women | W | 2-0 |
| Guatemala Liga Nacional Women | 2022/05/08 21:00 | FCF El Estor Women v Antigua GFC Women | W | 0-1 |
| Guatemala Liga Nacional Women | 2022/04/10 17:00 | K’iche FC Women v Antigua GFC Women | W | 0-1 |
| Guatemala Liga Nacional Women | 2022/03/27 21:00 | Antigua GFC Women v Deportivo Mixco Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2022/02/20 21:00 | Antigua GFC Women v CSD Barcena FF Women | W | 2-1 |
| Guatemala Liga Nacional Women | 2022/02/14 00:00 | Deportivo Mixco Women v Antigua GFC Women | L | 3-2 |
| Guatemala Liga Nacional Women | 2022/02/06 17:00 | Antigua GFC Women v Tunecas Women | D | 1-1 |
| Guatemala Liga Nacional Women | 2021/11/14 17:10 | Antigua GFC Women v Xinabajul Women | L | 0-4 |