| Colombia Regional League | 2022/08/30 15:00 | Medellin City FC v FC Leones Reserves | L | 4-0 |
| Colombia Regional League | 2023/06/21 15:00 | FC Leones Reserves v Talento y Vida | W | 5-4 |
| Colombia Regional League | 2023/06/05 13:11 | FC Leones Reserves v Soccer Law | W | 3-2 |
| Colombia Regional League | 2023/05/22 21:16 | FC Leones Reserves v Universidad de Antioquia | W | 3-2 |
| Colombia Regional League | 2023/05/16 16:00 | Sellos Colombianos v FC Leones Reserves | W | 4-6 |
| Colombia Regional League | 2023/04/17 15:00 | FC Leones Reserves v CD Gallegol | L | 2-4 |
| Colombia Regional League | 2023/03/27 13:00 | Rojo FC v FC Leones Reserves | L | 6-1 |
| Colombia Regional League | 2023/03/13 18:12 | Molino Viejo v FC Leones Reserves | L | 2-1 |
| Colombia Regional League | 2023/03/07 15:00 | FC Leones Reserves v Envigado FC Reserves | L | 1-3 |
| Colombia Regional League | 2023/06/27 15:15 | Medellin City FC v Rojo FC | W | 2-0 |
| Colombia Regional League | 2023/06/18 21:22 | Total Soccer FC v Medellin City FC | W | 1-3 |
| Colombia Regional League | 2023/06/15 15:14 | Medellin City FC v Molino Viejo | L | 1-2 |
| Colombia Regional League | 2023/06/07 13:12 | Envigado FC Reserves v Medellin City FC | L | 3-1 |
| Colombia Regional League | 2023/04/21 15:00 | Medellin City FC v Real Santuario | D | 2-2 |
| Colombia Regional League | 2023/03/28 15:13 | Medellin City FC v Talento y Vida | W | 2-0 |
| Colombia Regional League | 2023/03/06 14:16 | Lula FC v Medellin City FC | L | 2-1 |
| Colombia Regional League | 2022/10/24 15:00 | Deportivo Alexis Garcia v Medellin City FC | W | 0-3 |