Stadium: Seaverns Field at Harold Alfond Stadium Round: 1
| NCAAF | 2022/10/29 17:00 | Middlebury Panthers v Colby Mules | L | 20-17 |
| NCAAF | 2021/10/16 17:00 | Colby Mules v Middlebury Panthers | W | 28-14 |
| NCAAF | 2019/10/12 17:00 | Middlebury Panthers v Colby Mules | L | 27-26 |
| NCAAF | 2018/09/29 17:00 | Colby Mules v Middlebury Panthers | L | 14-31 |
| NCAAF | 2023/11/11 22:00 | Colby Mules v Bowdoin Polar Bears | L | 14-35 |
| NCAAF | 2023/11/04 17:00 | Tufts Jumbos v Colby Mules | L | 38-0 |
| NCAAF | 2023/10/21 17:00 | Colby Mules v Hamilton Continentals | L | 6-17 |
| NCAAF | 2023/10/14 17:00 | Amherst Mammoths v Colby Mules | W | 16-19 |
| NCAAF | 2023/10/07 17:00 | Colby Mules v Wesleyan Cardinals | W | 20-13 |
| NCAAF | 2023/09/30 22:00 | Bates Bobcats v Colby Mules | W | 24-30 |
| NCAAF | 2023/09/23 17:00 | Colby Mules v Trinity Bantams | L | 7-48 |
| NCAAF | 2023/09/16 17:00 | Williams Ephs v Colby Mules | L | 25-22 |
| NCAAF | 2023/11/11 17:30 | Middlebury Panthers v Tufts Jumbos | W | 19-10 |
| NCAAF | 2023/11/04 16:30 | Hamilton Continentals v Middlebury Panthers | W | 7-41 |
| NCAAF | 2023/10/21 17:00 | Middlebury Panthers v Bates Bobcats | W | 48-7 |
| NCAAF | 2023/10/14 17:00 | Trinity Bantams v Middlebury Panthers | W | 15-20 |
| NCAAF | 2023/10/07 18:00 | Williams Ephs v Middlebury Panthers | W | 10-12 |
| NCAAF | 2023/09/30 17:00 | Middlebury Panthers v Bowdoin Polar Bears | W | 34-27 |
| NCAAF | 2023/09/23 17:00 | Wesleyan Cardinals v Middlebury Panthers | L | 24-21 |
| NCAAF | 2023/09/16 18:00 | Middlebury Panthers v Amherst Mammoths | W | 21-7 |