Stadium: Mohegan Sun Arena Round: 1
Home Manager: Jamion Christian Away Manager: Bill Carmody
| NCAAB | 2017/12/23 00:00 | Siena v Holy Cross | L | 71-65 |
| NCAAB | 2008/12/30 12:00 | Holy Cross v Siena | L | 71-83 |
| NCAAB | 2007/12/22 12:00 | Siena v Holy Cross | L | 84-77 |
| NCAAB | 2006/11/18 12:00 | Holy Cross v Siena | W | 65-57 |
| NCAAB | 2005/12/01 12:00 | Siena v Holy Cross | L | 68-63 |