| Australian Open | 01/21 01:00 | 23 | Miomir Kecmanovic v Andreas Seppi | View | |
| ATP Auckland | 01/15 05:05 | 26 | [84] Andreas Seppi v Kyle Edmund [69] | 3-6,6-7 | |
| ATP Auckland | 01/14 22:00 | 25 | [43] Adrian Mannarino v Andreas Seppi [84] | 6-3,4-6,4-6 | |
| ATP Adelaide | 01/10 23:30 | 64 | Andreas Seppi v Bradley Mousley | Cancelled | |
| Challenger Canberra | 01/08 03:50 | 25 | [209] Zhe Li v Andreas Seppi [71] | 3-6,7-5,6-4 | |
| ATP Paris | 10/29 15:25 | 25 | [50] Radu Albot v Andreas Seppi [74] | 7-6,7-6 | |
| ATP Paris | 10/27 12:30 | 64 | [71] Andreas Seppi v Yoshihito Nishioka [68] | 3-6,6-3,5-7 | |
| ATP Paris | 10/26 14:40 | 45 | [51] Alexander Bublik v Andreas Seppi [71] | 6-7,5-7 | |
| ATP Moscow | 10/19 15:10 | 28 | [44] Adrian Mannarino v Andreas Seppi [72] | 6-3,6-4 | |
| ATP Moscow | 10/18 13:30 | 27 | [72] Andreas Seppi v Karen Khachanov [8] | 3-6,6-3,6-3 | |
| ATP Moscow | 10/16 09:30 | 26 | [72] Andreas Seppi v Roberto Carballes Baena [80] | 5-7,6-1,6-3 | |
| ATP Moscow | 10/14 11:55 | 25 | Cristian Garin v Andreas Seppi | 6-3,6-7,6-7 | |
| ATP Beijing | 09/28 09:00 | 64 | [223] Vasek Pospisil v Andreas Seppi [74] | 6-3,6-4 | |
| ATP Zhuhai | 09/27 09:10 | 27 | [74] Andreas Seppi v Roberto Bautista-Agut [10] | 2-6,2-6 | |
| ATP Zhuhai | 09/26 05:30 | 26 | [74] Andreas Seppi v Zhizhen Zhang [224] | 7-6,4-6,7-6 | |
| ATP Zhuhai | 09/25 07:15 | 25 | [27] Nick Kyrgios v Andreas Seppi [74] | 6-7,1-6 | |
| Challenger Cary | 09/15 17:00 | 29 | [77] Andreas Seppi v Michael Mmoh [186] | 6-2,6-7,6-3 | |
| Challenger Cary | 09/14 19:15 | 28 | [77] Andreas Seppi v Enzo Couacaud [207] | 4-6,7-6,6-4 | |
| Challenger Cary | 09/13 21:00 | 27 | [77] Andreas Seppi v Noah Rubin [175] | 6-0,6-4 | |
| Challenger Cary | 09/12 18:30 | 26 | [77] Andreas Seppi v John-Patrick Smith [247] | 6-3,6-2 | |
| Challenger Cary | 09/11 23:05 | 25 | [77] Andreas Seppi v Liam Broady [266] | 7-6,6-3 | |
| Challenger New Haven | 09/06 17:15 | 27 | [77] Andreas Seppi v Noah Rubin [195] | 6-7,6-7 | |
| Challenger New Haven | 09/05 14:00 | 26 | [77] Andreas Seppi v Peter Polansky [192] | 6-7,6-1,6-3 | |
| Challenger New Haven | 09/04 17:00 | 25 | [77] Andreas Seppi v Roy Smith [327] | 7-6,6-3 | |
| US Open | 08/26 18:55 | 23 | [77] Andreas Seppi v Grigor Dimitrov [78] | 1-6,7-6,4-6,3-6 | |
| ATP Winston-Salem | 08/18 23:00 | 24 | [103] Tomas Berdych v Andreas Seppi [78] | 6-1,3-6,6-3 | |
| Wimbledon | 07/03 14:15 | 24 | [73] Andreas Seppi v Guido Pella [26] | 4-6,6-4,6-4,5-7,1-6 | |
| Wimbledon | 07/01 11:45 | 23 | [73] Andreas Seppi v Nicolas Jarry [53] | 6-3,6-7,6-1,6-2 | |
| ATP Antalya | 06/24 13:55 | 25 | [71] Andreas Seppi v Bernard Tomic [101] | 6-4,4-6,4-6 | |
| ATP Halle | 06/20 10:00 | 26 | [22] Matteo Berrettini v Andreas Seppi [69] | 4-6,6-3,6-2 |