| Date | R | Home v Away | - | |
|---|---|---|---|---|
| 05/16 22:00 | - | Louisville v Northern Kentucky | W | 18-5 |
| 05/14 17:00 | - | Virginia v Louisville | L | 8-3 |
| 05/13 23:00 | - | Virginia v Louisville | L | 4-1 |
| 05/12 22:00 | - | Virginia v Louisville | L | 15-5 |
| 05/09 22:00 | - | Louisville v Vanderbilt | L | 8-12 |
| 05/07 16:00 | - | Clemson v Louisville | L | 7-3 |
| 05/06 18:00 | - | Clemson v Louisville | L | 4-3 |
| 05/05 20:00 | - | Clemson v Louisville | L | 6-3 |
| 05/02 22:00 | - | Bellarmine v Louisville | W | 7-18 |
| 04/29 17:00 | - | [8] Miami Florida v Louisville [4] | L | 10-7 |
| 04/28 22:00 | - | [7] Miami Florida v Louisville [4] | W | 0-11 |
| 04/27 20:00 | - | [7] Miami Florida v Louisville [4] | L | 6-5 |
| 04/25 23:00 | - | Louisville v Kentucky | W | 7-0 |
| 04/23 17:00 | - | Duke v Louisville | L | 4-3 |
| 04/22 23:00 | - | Louisville v Duke | L | 6-7 |
| 04/21 22:00 | - | Duke v Louisville | L | 10-9 |
| 04/18 22:00 | - | [3] Louisville v Indiana [3] | L | 3-7 |
| 04/16 17:00 | - | [1] Wake Forest v Louisville [3] | W | 2-7 |
| 04/15 17:00 | - | [1] Wake Forest v Louisville [3] | L | 3-0 |
| 04/14 22:00 | - | [2] Wake Forest v Louisville [3] | L | 11-5 |
| 04/12 23:00 | - | Louisville v Bellarmine | W | 14-2 |
| 04/08 16:00 | - | [4] Wake Forest v Louisville [3] | W | 2-4 |
| 04/07 22:00 | - | [4] Boston College v Louisville [3] | W | 8-9 |
| 04/06 22:00 | - | [4] Boston College v Louisville [3] | W | 4-6 |
| 04/04 22:00 | - | [11] Lipscomb v Louisville [3] | L | 12-7 |
| 04/02 16:00 | - | NC State v Louisville | W | 1-6 |
| 04/01 22:00 | - | NC State v Louisville | L | 10-0 |
| 03/31 22:00 | - | NC State v Louisville | L | 6-5 |
| 03/28 22:00 | - | Cincinnati v Louisville | W | 1-14 |
| 03/26 19:00 | - | Notre Dame v Louisville | W | 1-2 |