| Date | R | Home v Away | - | |
|---|---|---|---|---|
| 09/02 17:00 | 7 | [9] Santos Laguna U23 v Unam Pumas U23 [8] | W | 2-0 |
| 08/30 15:00 | 5 | Tigres UANL U23 v Santos Laguna U23 | D | 1-1 |
| 08/26 17:00 | 6 | [8] Santos Laguna U23 v Chivas Guadalajara U23 [5] | L | 0-1 |
| 07/13 17:00 | 3 | Santos Laguna U23 v Atlas U23 | W | 2-1 |
| 07/07 15:00 | 2 | Puebla U23 v Santos Laguna U23 | L | 4-0 |
| 07/02 17:00 | 1 | Santos Laguna U23 v Queretaro U23 | W | 4-3 |