Head to Head
| Mexico Liga MX | 2016/02/21 18:00 | Unam Pumas v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2015/08/29 02:30 | Santos Laguna v Unam Pumas | W | 3-4 |
| Mexico Liga MX | 2015/04/19 17:00 | Unam Pumas v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2014/10/25 02:30 | Santos Laguna v Unam Pumas | D | 1-1 |
Home History
| Copa Libertadores Qualification | 2016/05/25 00:45 | Unam Pumas v Independiente del Valle | L | 5-6 |
| Copa Libertadores Qualification | 2016/05/18 00:45 | Independiente del Valle v Unam Pumas | L | 2-1 |
| Mexico Liga MX | 2016/05/08 17:00 | Unam Pumas v Club America | D | 1-1 |
| Copa Libertadores Qualification | 2016/05/04 02:45 | Unam Pumas v Deportivo Tachira | W | 2-0 |
| Mexico Liga MX | 2016/04/30 00:30 | Queretaro v Unam Pumas | L | 2-1 |
| Copa Libertadores Qualification | 2016/04/27 00:45 | Deportivo Tachira v Unam Pumas | L | 1-0 |
| Mexico Liga MX | 2016/04/23 01:00 | Unam Pumas v Tijuana | W | 3-1 |
| Mexico Liga MX | 2016/04/17 02:00 | Chiapas v Unam Pumas | W | 1-2 |
Away History
| World Club Friendlies | 2016/06/25 02:00 | Santos Laguna v Tijuana | L | 1-2 |
| World Club Friendlies | 2016/06/22 00:30 | Santos Laguna v Pachuca | D | 1-1 |
| Mexico Liga MX | 2016/05/16 01:06 | Pachuca v Santos Laguna | L | 3-2 |
| Mexico Liga MX | 2016/05/13 00:00 | Santos Laguna v Pachuca | D | 1-1 |
| Mexico Liga MX | 2016/05/07 02:30 | Santos Laguna v Chivas Guadalajara | L | 0-1 |
| Mexico Liga MX | 2016/05/01 01:30 | Mazatlan FC v Santos Laguna | L | 3-2 |
| Mexico Liga MX | 2016/04/24 00:00 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexico Liga MX | 2016/04/16 22:00 | Cruz Azul v Santos Laguna | W | 0-1 |
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