| ATP Shanghai Qual | 10/07 04:00 | 45 | [118] Mikhail Youzhny v Malek Jaziri [90] | 2-6,4-6 | |
| Challenger Kaohsiung | 10/03 07:45 | 25 | [362] Luke Saville v Mikhail Youzhny [118] | 1-6,7-6,6-1 | |
| ATP St Petersburg | 09/21 13:50 | 26 | [29] Fabio Fognini v Mikhail Youzhny [112] | 6-4,4-6,6-4 | |
| ATP St Petersburg | 09/19 13:30 | 25 | [185] John-Patrick Smith v Mikhail Youzhny [112] | 6-7,4-6 | |
| US Open | 08/31 19:05 | 24 | [3] Roger Federer v Mikhail Youzhny [101] | 6-1,6-7,4-6,6-4,6-2 | |
| US Open | 08/30 15:00 | 23 | [88] Blaz Kavcic v Mikhail Youzhny [101] | 3-6,7-5,4-6,3-6 | |
| ATP Cincinnati | 08/15 16:40 | 24 | Albert Ramos-Vinolas v Mikhail Youzhny | 6-2,3-6,6-3 | |
| ATP Cincinnati Qual | 08/13 16:00 | 46 | [275] Ernests Gulbis v Mikhail Youzhny [98] | 6-4,1-6,4-6 | |
| ATP Cincinnati Qual | 08/12 17:35 | 45 | Radu Albot v Mikhail Youzhny | 6-4,4-6,0-6 | |
| ATP Montreal | 08/08 16:30 | 24 | [55] Borna Coric v Mikhail Youzhny [98] | 6-2,6-4 | |
| ATP Montreal Qual | 08/06 15:45 | 46 | [68] Pierre-Hugues Herbert v Mikhail Youzhny [99] | 6-2,2-6,6-3 | |
| ATP Montreal Qual | 08/05 17:25 | 45 | [259] Lloyd Harris v Mikhail Youzhny [99] | 6-7,7-6,6-7 | |
| ATP Kitzbuhel | 07/31 09:00 | 25 | [62] Joao Sousa v Mikhail Youzhny [99] | 6-7,7-5,6-3 | |
| ATP Gstaad | 07/25 08:00 | 25 | [85] Mikhail Youzhny v Radu Albot [132] | 6-4,6-7,5-7 | |
| ATP Umag | 07/18 18:20 | 25 | [76] Mikhail Youzhny v Nicolas Kicker [95] | 3-6,5-7 | |
| Wimbledon | 07/06 15:40 | 24 | [7] Milos Raonic v Mikhail Youzhny [82] | 3-6,7-6,6-4,7-5 | |
| Wimbledon | 07/04 10:30 | 23 | [82] Mikhail Youzhny v Nicolas Mahut [78] | 6-2,7-5,6-4 | |
| ATP Halle | 06/22 11:20 | 26 | [88] Mikhail Youzhny v Andrey Rublev [106] | 0-6,6-3,3-6 | |
| ATP Halle | 06/20 16:00 | 25 | [24] Ivo Karlovic v Mikhail Youzhny [88] | 3-6,6-7 | |
| ATP Halle Qual | 06/18 11:00 | 46 | [64] Yuichi Sugita v Mikhail Youzhny [86] | 6-7,7-6,6-7 | |
| ATP Halle Qual | 06/17 13:00 | 45 | [170] Benjamin Becker v Mikhail Youzhny [86] | 3-6,4-6 | |
| ATP Den Bosch | 06/13 10:25 | 25 | [86] Mikhail Youzhny v Thanasi Kokkinakis [245] | 4-6,5-7 | |
| French Open | 05/29 11:40 | 23 | [79] Rogerio Dutra Silva v Mikhail Youzhny [86] | 4-6,7-6,2-6,7-6,6-2 | |
| ATP Madrid Qual | 05/07 15:05 | 46 | [57] Thomaz Bellucci v Mikhail Youzhny [88] | 6-2,6-3 | |
| ATP Madrid Qual | 05/06 15:05 | 45 | [127] Roberto Carballes Baena v Mikhail Youzhny [88] | 6-3,3-6,4-6 | |
| ATP Istanbul | 05/04 11:15 | 26 | [84] Dusan Lajovic v Mikhail Youzhny [88] | 3-6,6-0,6-3 | |
| ATP Istanbul | 05/01 14:00 | 25 | [88] Mikhail Youzhny v Cem Ilkel [323] | 3-6,6-3,6-3 | |
| ATP Budapest | 04/25 13:50 | 25 | [154] Marton Fucsovics v Mikhail Youzhny [89] | 6-2,6-2 | |
| ATP Monte Carlo Qual | 04/16 10:45 | 46 | [71] Andrey Kuznetsov v Mikhail Youzhny [88] | 3-6,7-6,7-6 | |
| ATP Monte Carlo Qual | 04/15 12:15 | 45 | [96] Taro Daniel v Mikhail Youzhny [88] | 3-6,6-1,6-7 |