| ATP Miami | 03/23 23:25 | 23 | [87] Mikhail Youzhny v Mikhail Kukushkin [76] | 4-6,1-6 | |
| ATP Miami Qual | 03/21 15:00 | 45 | [87] Mikhail Youzhny v Benjamin Becker [163] | 6-1,3-6,2-6 | |
| ATP Miami Qual | 03/20 16:35 | 44 | [87] Mikhail Youzhny v Vincent Millot [167] | 6-4,4-6,7-6 | |
| ATP Indian Wells | 03/12 20:35 | 24 | [84] Mikhail Youzhny v Grigor Dimitrov [13] | 4-6,0-6 | |
| ATP Indian Wells | 03/10 19:00 | 23 | [58] Daniil Medvedev v Mikhail Youzhny [84] | 4-6,4-6 | |
| ATP Dubai | 02/28 10:00 | 25 | Mikhail Youzhny v Evgeny Donskoy | 4-6,4-6 | |
| ATP Marseille | 02/22 16:00 | 26 | [87] Mikhail Youzhny v Richard Gasquet [19] | 5-7,2-6 | |
| ATP Marseille | 02/20 13:55 | 25 | Stefanos Tsitsipas v Mikhail Youzhny | 1-6,6-4,5-7 | |
| ATP Rotterdam Qual | 02/11 10:00 | 45 | Mikhail Youzhny v Evgeny Donskoy | Retired | |
| ATP Sofia | 02/09 10:00 | 26 | [29] Gilles Muller v Mikhail Youzhny [89] | 6-3,7-5 | |
| ATP Sofia | 02/07 11:40 | 25 | Marko Tepavac v Mikhail Youzhny | 6-7,4-6 | |
| Australian Open 2017 | 01/17 04:00 | 23 | Mikhail Youzhny v Marcos Baghdatis | Retired | |
| Kooyong Classic | 01/12 03:55 | 1 | Mikhail Youzhny v Marc Polmans | 6-2,2-6,9-11 | |
| Kooyong Classic | 01/11 00:00 | 1 | Mikhail Youzhny v Andrew Whittington | Retired | |
| ATP Chennai | 01/06 14:55 | 27 | [57] Mikhail Youzhny v Roberto Bautista-Agut [14] | 6-2,4-6,4-6 | |
| ATP Chennai | 01/05 11:30 | 26 | [57] Mikhail Youzhny v Renzo Olivo [83] | 6-1,7-5 | |
| ATP Chennai | 01/03 14:30 | 25 | Mikhail Youzhny v Saketh Myneni | 6-4,6-3 | |
| Challenger Mouilleron le Captif | 11/08 20:05 | 25 | Julien Benneteau v Mikhail Youzhny | 6-4,6-7,7-6 | |
| ATP Paris Qual | 10/29 16:10 | 45 | Mikhail Youzhny v Pierre-Hugues Herbert | 6-4,2-6,2-6 | |
| ATP Basel | 10/24 18:15 | 25 | [12] Marin Cilic v Mikhail Youzhny [51] | 6-4,6-2 | |
| ATP Antwerp | 10/18 12:10 | 25 | [98] Jan-Lennard Struff v Mikhail Youzhny [49] | 6-7,6-3,6-0 | |
| ATP Shanghai | 10/10 12:00 | 24 | [51] Mikhail Youzhny v Nicolas Almagro [45] | 6-3,2-6,2-6 | |
| ATP Shanghai Qual | 10/09 04:00 | 46 | Mikhail Youzhny v Michael Berrer | 6-2,6-2 | |
| ATP Shanghai Qual | 10/08 06:15 | 45 | Mikhail Youzhny v Bowen Ouyang | 6-3,6-1 | |
| Others | 10/01 03:00 | 45 | Mikhail Youzhny v Matthew Ebden | 2-6,2-6 | |
| ATP St Petersburg | 09/23 13:40 | 27 | Alexander Zverev v Mikhail Youzhny | 6-2,6-2 | |
| ATP St Petersburg | 09/22 15:40 | 26 | Mikhail Youzhny v Milos Raonic | 2-6,7-6,6-4 | |
| ATP St Petersburg | 09/21 10:20 | 25 | Janko Tipsarevic v Mikhail Youzhny | 3-6,5-7 | |
| US Open 2016 | 09/02 19:30 | 25 | Novak Djokovic v Mikhail Youzhny | Retired | |
| US Open 2016 | 08/31 19:10 | 24 | Guido Pella v Mikhail Youzhny | 2-6,1-6,6-7 |