| Argentina Reserve League | 10/10 13:00 | 24 | [2] Velez Sarsfield Reserves v San Lorenzo Reserves [18] | L | 2-0 | |
| Argentina Reserve League | 10/04 14:00 | 23 | [15] San Lorenzo Reserves v Godoy Cruz Reserves [19] | L | 0-1 | |
| Argentina Reserve League | 09/28 13:00 | 22 | [5] Huracan Reserves v San Lorenzo Reserves [15] | L | 3-1 | |
| Argentina Reserve League | 09/25 14:00 | 21 | [13] San Lorenzo Reserves v Lanus Reserves [14] | L | 1-2 | |
| Argentina Reserve League | 09/19 13:00 | 20 | [9] River Plate Reserves v San Lorenzo Reserves [11] | L | 1-0 | |
| Argentina Reserve League | 09/12 13:00 | 19 | [11] San Lorenzo Reserves v Colon Reserves [15] | W | 2-1 | |
| Argentina Reserve League | 09/07 14:00 | 18 | [19] Atletico Tucuman Reserves v San Lorenzo Reserves [13] | W | 1-2 | |
| Argentina Reserve League | 09/01 14:00 | 17 | [17] San Lorenzo Reserves v Defensa y Justicia Reserves [8] | W | 1-0 | |
| Argentina Reserve League | 08/28 13:00 | 16 | [9] Rosario Central Reserves v San Lorenzo Reserves [19] | W | 0-1 | |
| Argentina Reserve League | 08/23 13:00 | 15 | [23] San Lorenzo Reserves v Racing Club Reserves [15] | W | 2-0 | |
| Argentina Reserve League | 08/17 13:00 | 14 | [26] Platense Reserves v San Lorenzo Reserves [21] | D | 0-0 | |
| Argentina Reserve League | 08/12 13:00 | 13 | [20] San Lorenzo Reserves v Patronato Parana Reserves [26] | L | 1-2 | |
| Argentina Reserve League | 08/08 13:00 | 12 | [26] Estudiantes LP Reserves v San Lorenzo Reserves [17] | L | 4-2 | |
| Argentina Reserve League | 08/01 13:00 | 11 | [16] San Lorenzo Reserves v Argentinos Jrs Reserves [13] | L | 3-4 | |
| Argentina Reserve League | 07/24 13:00 | 10 | [19] CA Talleres de Córdoba Reserves v San Lorenzo Reserves [21] | W | 1-3 | |
| Argentina Reserve League | 07/19 14:00 | 9 | [18] Union Santa Fe Reserves v San Lorenzo Reserves [19] | D | 0-0 | |
| Argentina Reserve League | 07/13 13:00 | 8 | [15] San Lorenzo Reserves v Banfield Reserves [23] | L | 0-1 | |
| Argentina Reserve League | 07/08 13:00 | 7 | [22] Boca Juniors Reserves v San Lorenzo Reserves [10] | L | 2-1 | |
| Argentina Reserve League | 07/03 13:00 | 6 | [17] San Lorenzo Reserves v Barracas Central Reserves [10] | W | 1-0 | |
| Argentina Reserve League | 06/25 13:00 | 5 | [25] CA Tigre Reserves v San Lorenzo Reserves [13] | L | 3-2 | |
| Argentina Reserve League | 06/20 12:00 | 4 | [12] San Lorenzo Reserves v Central Cordoba SdE Reserves [23] | D | 0-0 | |
| Argentina Reserve League | 06/14 12:00 | 3 | [2] Arsenal de Sarandi Reserves v San Lorenzo Reserves [13] | W | 0-1 | |
| Argentina Reserve League | 06/09 12:00 | 2 | [9] San Lorenzo Reserves v Newell's Reserves [9] | L | 2-3 | |
| Argentina Reserve League | 06/05 13:15 | 1 | [15] CA Independiente Reserves v San Lorenzo Reserves [15] | W | 0-1 | |
| Argentina Reserve League | 05/09 12:00 | - | San Lorenzo Reserves v Racing Club Reserves | W | 3-1 | |
| Argentina Reserve League | 04/30 14:00 | - | Newell's Reserves v San Lorenzo Reserves | W | 0-3 | |
| Argentina Reserve League | 04/24 12:00 | - | San Lorenzo Reserves v Patronato Parana Reserves | W | 3-0 | |
| Argentina Reserve League | 04/20 13:00 | - | Union Santa Fe Reserves v San Lorenzo Reserves | W | 1-4 | |
| Argentina Reserve League | 04/15 12:00 | - | San Lorenzo Reserves v Platense Reserves | D | 1-1 | |
| Argentina Reserve League | 04/10 14:00 | - | Sarmiento Reserves v San Lorenzo Reserves | W | 1-2 |