[16] Serena Williams 4-6,6-4,5-7 Karolina Pliskova [8] 2019-01-23 02:00
Stadium: Rod Laver Arena Round: 27 Ground: Hardcourt outdoor
Head to Head
| US Open Women | 2018/09/04 23:10 | Serena Williams v Karolina Pliskova | 6-4,6-3 |
| US Open 2016 Women | 2016/09/08 23:00 | Serena Williams v Karolina Pliskova | 2-6,6-7 |
Home History
| Australian Open Women | 2019/01/21 08:00 | Simona Halep v Serena Williams | 1-6,6-4,4-6 |
| Australian Open Women | 2019/01/19 03:25 | Dayana Yastremska v Serena Williams | 2-6,1-6 |
| Australian Open Women | 2019/01/17 09:20 | Eugenie Bouchard v Serena Williams | 2-6,2-6 |
| Australian Open Women | 2019/01/15 01:35 | Tatjana Maria v Serena Williams | 0-6,2-6 |
| Hopman Cup Women | 2019/01/03 03:30 | Katie Boulter v Serena Williams | 1-6,6-7 |
| Hopman Cup Women | 2019/01/01 10:45 | Serena Williams v Belinda Bencic | 4-6,6-4,6-3 |
| Hopman Cup Women | 2018/12/31 04:30 | Serena Williams v Maria Sakkari | 7-6,6-2 |
| Mubadala World Tennis Championship Women | 2018/12/27 16:05 | Serena Williams v Venus Williams | 6-4,3-6,8-10 |
Away History
| Australian Open Women | 2019/01/21 05:00 | Garbine Muguruza v Karolina Pliskova | 3-6,1-6 |
| Australian Open Women | 2019/01/19 10:20 | Camila Giorgi v Karolina Pliskova | 4-6,6-3,2-6 |
| Australian Open Women | 2019/01/17 00:00 | Madison Brengle v Karolina Pliskova | 6-4,1-6,0-6 |
| Australian Open Women | 2019/01/15 00:00 | Karolina Muchova v Karolina Pliskova | 3-6,2-6 |
| WTA Brisbane | 2019/01/06 07:00 | Karolina Pliskova v Lesia Tsurenko | 4-6,7-5,6-2 |
| WTA Brisbane | 2019/01/05 09:00 | Donna Vekic v Karolina Pliskova | 3-6,4-6 |
| WTA Brisbane | 2019/01/04 09:00 | Ajla Tomljanovic v Karolina Pliskova | 1-6,6-1,1-6 |
| WTA Brisbane | 2019/01/02 06:05 | Marie Bouzkova v Karolina Pliskova | 5-7,2-6 |
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