| ATP Budapest | 04/25 13:25 | 25 | [50] Ryan Harrison v Andrey Kuznetsov [87] | 6-7,3-6 | |
| ATP Monte Carlo | 04/18 09:00 | 24 | [17] Lucas Pouille v Ryan Harrison [50] | 6-2,6-4 | |
| ATP Miami | 03/22 16:35 | 23 | [40] Fabio Fognini v Ryan Harrison [47] | 6-4,7-5 | |
| ATP Indian Wells | 03/10 05:45 | 23 | [67] Damir Dzumhur v Ryan Harrison [45] | 6-4,3-6,7-5 | |
| ATP Acapulco Qual | 02/26 23:30 | - | [43] Ryan Harrison v Yoshihito Nishioka [91] | 6-3,3-6,2-6 | |
| ATP Acapulco Qual | 02/25 23:05 | 26 | Ryan Harrison v Matthew Ebden | 6-3,6-3 | |
| ATP Memphis | 02/19 21:00 | 29 | [67] Nikoloz Basilashvili v Ryan Harrison [62] | 1-6,4-6 | |
| ATP Memphis | 02/19 01:30 | 28 | [62] Ryan Harrison v Donald Young [81] | 6-4,6-4 | |
| ATP Memphis | 02/18 04:20 | 27 | [86] Damir Dzumhur v Ryan Harrison [62] | 3-6,4-6 | |
| ATP Memphis | 02/16 03:40 | 26 | [62] Ryan Harrison v Sam Querrey [29] | 6-3,6-1 | |
| ATP Memphis | 02/14 21:00 | 25 | [62] Ryan Harrison v Konstantin Kravchuk [85] | 6-3,7-5 | |
| Challenger Dallas | 02/05 03:05 | 29 | [78] Ryan Harrison v Taylor Fritz [98] | 6-3,6-3 | |
| Challenger Dallas | 02/03 20:20 | 28 | Ryan Harrison v Tatsuma Ito | 6-3,6-0 | |
| Challenger Dallas | 02/02 19:55 | 27 | Ryan Harrison v Marco Trungelliti | 6-4,6-1 | |
| Challenger Dallas | 02/01 23:50 | 26 | Ryan Harrison v Mackenzie McDonald | 6-2,7-6 | |
| Challenger Dallas | 01/31 02:40 | 25 | Ryan Harrison v Eric Quigley | 6-3,6-4 | |
| Australian Open 2017 | 01/18 03:10 | 24 | [10] Tomas Berdych v Ryan Harrison [82] | 6-3,7-6,6-2 | |
| Australian Open 2017 | 01/16 00:00 | 23 | [89] Ryan Harrison v Nicolas Mahut [38] | 6-3,6-4,6-2 | |
| ATP Auckland | 01/11 06:25 | 26 | [89] Ryan Harrison v Jack Sock [23] | 6-7,6-4,1-6 | |
| ATP Auckland | 01/09 23:30 | 25 | [89] Ryan Harrison v Guillermo Garcia-Lopez [73] | 6-1,6-2 | |
| ATP Auckland Qual | 01/07 23:00 | 46 | Ryan Harrison v Jose Statham | 6-4,6-1 | |
| ATP Auckland Qual | 01/07 00:50 | 45 | Ryan Harrison v Marcin Matkowski | 6-4,6-4 | |
| ATP Brisbane Qual | 12/31 06:15 | - | Ryan Harrison v Ivan Dodig | 4-6,6-4,4-6 | |
| ATP Paris Qual | 10/30 12:15 | 46 | Pierre-Hugues Herbert v Ryan Harrison | Retired | |
| ATP Paris Qual | 10/29 15:10 | 45 | [98] Ryan Harrison v Taylor Fritz [73] | 7-6,4-6,6-3 | |
| ATP Basel Qual | 10/23 13:20 | 46 | Mischa Zverev v Ryan Harrison | 7-6,6-3 | |
| ATP Basel Qual | 10/22 12:35 | 45 | Johan Nikles v Ryan Harrison | 1-6,2-6 | |
| ATP Stockholm | 10/20 10:00 | 26 | Kevin Anderson v Ryan Harrison | 7-6,6-4 | |
| ATP Stockholm | 10/17 12:00 | 25 | Adam Pavlasek v Ryan Harrison | 3-6,5-7 | |
| ATP Stockholm Qual | 10/16 10:35 | 46 | Ryan Harrison v Matthias Bachinger | 7-6,6-2 |