| ATP Barcelona | 04/20 10:10 | 45 | [117] Guillermo Garcia-Lopez v Carlos Berlocq [179] | 6-4,6-3 | |
| ATP Barcelona | 04/20 09:20 | 45 | Guillermo Garcia-Lopez v Pablo Andujar | Cancelled | |
| Challenger Tunis | 04/17 10:45 | 25 | [221] Joao Domingues v Guillermo Garcia-Lopez [117] | 6-4,5-7,6-4 | |
| ATP Houston | 04/11 18:35 | 26 | [71] Sam Querrey v Guillermo Garcia-Lopez [115] | 6-4,6-3 | |
| ATP Houston | 04/09 19:20 | 25 | [115] Guillermo Garcia-Lopez v Noah Rubin [144] | 6-7,6-3,6-3 | |
| Challenger Alicante | 04/04 09:30 | 26 | [113] Guillermo Garcia-Lopez v Carlos Taberner [301] | 7-6,1-6,4-6 | |
| Challenger Alicante | 04/02 17:10 | 25 | [113] Guillermo Garcia-Lopez v Pedro Cachin [236] | 6-0,6-4 | |
| Challenger Marbella | 03/28 13:35 | 26 | [158] Pedro Martinez v Guillermo Garcia-Lopez [112] | 3-6,6-3,6-1 | |
| Challenger Marbella | 03/26 11:45 | 25 | [187] Enrique Lopez-Perez v Guillermo Garcia-Lopez [112] | 6-4,5-7,5-7 | |
| Challenger Lille | 03/19 17:50 | 25 | [112] Guillermo Garcia-Lopez v Adam Pavlasek [222] | 5-7,6-7 | |
| ATP Acapulco | 02/27 00:30 | 25 | [57] Sam Querrey v Guillermo Garcia-Lopez [103] | 6-3,6-2 | |
| ATP Acapulco | 02/25 01:00 | 164 | [101] Guillermo Garcia-Lopez v Marcel Granollers [111] | 4-6,6-3,1-6 | |
| ATP Acapulco | 02/24 01:20 | 64 | [101] Guillermo Garcia-Lopez v Roberto Cid Subervi [246] | 6-3,6-3 | |
| ATP Delray Beach | 02/21 23:30 | 26 | [101] Guillermo Garcia-Lopez v Mackenzie McDonald [84] | 5-7,4-6 | |
| ATP Delray Beach | 02/19 16:00 | 25 | [101] Guillermo Garcia-Lopez v Jared Donaldson [120] | 2-6,6-3,6-3 | |
| ATP New York | 02/15 21:50 | 27 | [102] Guillermo Garcia-Lopez v Reilly Opelka [89] | 3-6,4-6 | |
| ATP New York | 02/14 16:00 | 26 | [37] John Millman v Guillermo Garcia-Lopez [102] | 6-7,6-1,4-6 | |
| ATP New York | 02/12 18:15 | 25 | [102] Guillermo Garcia-Lopez v Alexei Popyrin [123] | 7-6,6-3 | |
| ATP New York | 02/12 17:20 | - | Guillermo Garcia-Lopez v Bradley Klahn | Cancelled | |
| Australian Open | 01/14 01:25 | 23 | [100] Guillermo Garcia-Lopez v Robin Haase [58] | 5-7,4-6,5-7 | |
| ATP Sydney | 01/09 02:00 | 26 | [19] Diego Schwartzman v Guillermo Garcia-Lopez [101] | 6-2,6-3 | |
| ATP Sydney | 01/08 00:00 | 25 | [62] Denis Kudla v Guillermo Garcia-Lopez [101] | 5-7,4-6 | |
| ATP Sydney | 01/06 07:05 | 164 | [105] Guillermo Garcia-Lopez v Alex Bolt [154] | 7-6,6-3 | |
| ATP Sydney | 01/05 03:20 | 64 | [67] Aljaz Bedene v Guillermo Garcia-Lopez [105] | 7-5,4-6,6-7 | |
| ATP Doha | 01/02 12:30 | 26 | [105] Guillermo Garcia Lopez v Roberto Bautista-Agut [24] | 1-6,4-6 | |
| ATP Doha | 01/01 14:35 | 25 | Mubarak Shannan Zayid v Guillermo Garcia Lopez | 1-6,3-6 | |
| ATP Doha | 12/30 12:30 | 164 | [105] Guillermo Garcia Lopez v Marcos Baghdatis [125] | 4-6,6-2,6-4 | |
| ATP Doha | 12/29 08:00 | 64 | [105] Guillermo Garcia Lopez v James Ward [190] | 7-6,6-2 | |
| ATP Doha | 12/29 08:00 | 64 | [105] Guillermo Garcia Lopez v Yannick Maden [127] | Cancelled | |
| Challenger Bratislava | 11/07 11:20 | 26 | [104] Guillermo Garcia-Lopez v Sebastian Ofner [203] | 5-7,4-6 |